Tumour Types

Brain Tumour Types

The term brain tumour is describing a wide variety of entities. The tumours differ through its growth, the expected prognosis and their response to therapy as well. Therefore, the accurate diagnosis and classification of a detected tumour has fundamental importance for its treatment. 
 

The exact diagnosis is made by using different imaging techniques and pathological examination of tumour tissue. The World Health Organization (WHO) distinguish four different tumour grades: 
 
WHO grade I    (benign)
WHO grade II   (still benign)
WHO grade III  (already malignant)
WHO grade IV  (malignant)

WHO grade I corresponds to a benign, slow-growing tumour. WHO grade IV, in contrast, is typically a particularly virulent and fast-growing tumour. Below is a selection of the most common brain tumours listed.

  Term of Brain Tumour Grading Code
       
1. Diffuse astrocytic and oligodendroglial tumours    
       
1.1. Diffuse astrocytoma, IDH-mutant  II 9400/3
1.1.1  • Gemistocytic astrocytoma, IDH-mutant   9411/3
1.2. Diffuse astrocytoma, IDH-wildtype   9400/3
1.3. Diffuse astrocytoma, NOS   9400/3
       
1.4. Anaplastic astrocytoma, IDH-mutant  III 9401/3
1.5. Anaplastic astrocytoma, IDH-wildtype   9401/3
1.6. Anaplastic astrocytoma, NOS   9401/3
       
1.7. Glioblastoma, IDH-wildtype  IV 9440/3
1.7.1.  • Giant cell glioblastoma   9441/3
1.7.2.  • Gliosarcoma   9442/3
1.7.3.  • Epitheloid glioblastoma   9440/3
1.8. Glioblastoma, IDH-mutant  IV 9445/3
1.9. Glioblastoma, NOS   9440/3
       
1.10. Diffuse midline glioma, H3 K27M-mutant  IV 9385/3
       
1.11. Oligodendroglioma, IDH-mutant and 1p/19q-codeleted  II 9450/3
1.12. Oligodendroglioma, NOS   9405/3
       
1.13. Anaplastic oligodendroglioma, IDH-mutant and 1p/19q-codeleted  III 9451/3
1.14. Anaplastic oligodendroglioma, NOS   9451/3
       
1.15. Oligoastrocytoma, NOS   9382/3
1.16. Anaplastic oligoastrocytoma, NOS   9382/3
       
       
2. Other astrocytic tumours    
       
2.1. Pilocytic astrocytoma  I 9421/1
2.1.1.  • Pilomyxoid astrocytoma   9425/3
2.2. Subependymal giant cell astrocytoma  I 9384/1
2.3. Pleomorphic xanthoastrocytoma  II 9424/3
2.4. Anaplastic pleomorphic xanthoastrocytoma  III 9424/3
       
       
3. Ependymal tumours    
       
3.1. Subependymoma  I 9383/1
3.2. Myxopapillary ependymoma  I 9394/1
3.3. Ependymoma  II 9391/3
3.3.1.  • Papillary ependymoma   9393/3
3.3.2.  • Clear cell ependymoma   9391/3
3.3.3.  • Tanycytic ependymoma   9391/3
3.4. Ependymoma, RELA fusion-positive  II/III 9396/3
3.5. Anaplastic ependymoma  III 9392/3
       
       
4. Other gliomas    
       
4.1. Chordoid glioma of the 3rd ventricle  II 9444/1
4.2. Angiocentric glioma  I 9431/1
4.3. Astroblastoma   9430/3
       
       
5.
Choroid plexus tumours    
       
5.1. Choroid plexus papilloma  I 9390/0
5.2. Atypical choroid plexus papilloma  II 9390/1
5.3. Choroid plexus carcinoma  III 9390/3
       
       
6.
Neuronal and neuronal-glial tumours    
       
6.1. Dysembryoplastic neuroepithelial tumour (DNT)  I 9413/0
6.2. Gangliocytoma  I 9492/0
6.3. Ganglioglioma  I 9505/1
6.4. Anaplastic ganglioglioma  III 9505/3
6.5. Dysplastic cerebellar gangliocytoma (Lhermitte-Duclos disease)  I 9493/0
6.6. Desmoplastic infantile astrocytoma/ganglioglioma  I 9412/1
6.7. Papillary glioneuronal tumour (PGNT)  I 9509/1
6.8. Rosette-forming glioneuronal tumour (RGNT)  I 9509/1
6.9. Diffuse leptomeningeal glioneuronal tumour    
6.10. Central neurocytoma  II 9506/1
6.11. Extraventricular neurocytoma  II 9506/1
6.12. Cerebellar liponeurocytoma  II 9506/1
6.13. Paraganglioma   8693/1
       
       
7.
Tumours of the pineal region    
       
7.1. Pineocytoma  I 9361/1
7.2. Pineal parenchymal tumour of intermediate differentation  II/III 9362/3
7.3. Pineoblastoma  IV 9362/3
7.4. Papillary tumour of the pineal region  II/III 9395/3
       
       
8.
Embryonal tumours    
       
8.1. Medulloblastomas, genetically defined  IV  
8.1.1.  • Medulloblastoma, WNT-activated  IV 9475/3
8.1.2.  • Medulloblastoma, WNT-activated and TP53-mutant  IV 9476/3
8.1.3.  • Medulloblastoma, SHH-activated and TP53-wldtype  IV 9471/3
8.1.4.  • Medulloblastoma, non-WNT/non-SHH  IV 9477/3
8.1.4.1.   ⇒ Medulloblastoma, group 3    
8.1.4.1.   ⇒ Medulloblastoma, group 4    
       
8.2. Medulloblastom, histologically defined  IV  
8.2.1.  • medulloblastoma, classic  IV 9470/3
8.2.2.  • medulloblastoma, desmoplastic/ nodular  IV 9471/3
8.2.3.  • medulloblastoma with extensive nodularity  IV 9471/3
8.2.4.  • medulloblastoma, large cell/anaplastic  IV 9474/3
       
8.3. Medulloblastoma, NOS  IV 9470/3
       
8.4. Embryonal tumour with multilayered rosettens, C19M-altered  IV 9478/3
8.5. Embryonal tumour with multilayered rosettes, NOS   9478/3
       
8.6. Medulloepithelioma  IV 9501/3
8.7. CNS neuroblastoma   9500/3
8.9. CNS ganglioneuroblastoma   9490/3
8.10. CNS Embryonal tumour, NOS  IV 9473/3
8.11. Atypical teratoid/rhabdoid tumour (ATRT)   9508/3
8.12. CNS Embryonal tumour with rhabdoid features  IV 9508/3
       
       
9.
Tumours of the cranial and paraspinal nerves    
       
9.1. Schwannoma  I 9560/0
9.1.1. •  Cellulat schwannoma   9560/0
9.1.2. •  Plexiform schwannoma   9560/0
9.2. Melanotic schwannoma   9560/1
9.3. Neurofibroma  I 9540/0
9.3.1. •  Atypical neurofibroma   9540/0
9.3.2. •  Plexiform neurofibroma   9550/0
9.4. Perineurioma  I 9571/0
9.5. Hybrid nerve sheath tumour    
9.6. Malignant peripheral nerve sheath tumour  II-IV  
9.6.1. •  Epitheloid malignant peripheral nerve sheath tumour   9540/3
9.6.2. •  Malignant peripheral nerve sheath tumour with perineurial differentiation   9540/3
      9540/3
       
10.   Meningeomas    
       
10.1. Meningeoma I 9530/0
10.2. Meningothelial meningeoma   9531/0
10.3. Fibrous meningeoma   9532/0
10.4. Transitional meningeoma   9537/0
10.5. Psammomatous meningeoma   9533/0
10.6. Angiomatous meningeoma   9534/0
10.7. Microcystic meningeoma   9530/0
10.8. Secretory meningeoma   9530/0
10.9. Lymphoplasmacyte-rich meningeoma   9530/0
10.10 Metaplastic meningeoma   9530/0
10.11. Chordoid meningeoma   9538/1
10.12. Clear cell meningeoma   9538/1
10.13. Atypical meningeoma  II 9539/1
10.14. Papillary meningeoma   9538/3
10.15. Rhabdoid meningeoma   9538/3
10.16. Anaplastic meningeoma  III 9530/3
       
       
11.
Mesenchymal, non-meningeothelial tumours    
       
11.1. Solitary fibrous tumour/haemangiopericytoma  I-III  
11.1.1.  •  Grade I   8815/0
11.1.2.  •  Grade II   8815/1
11.1.3.  •  Grade III   8815/3
11.2. Haemangioblastoma  I 9161/1
11.3. Haemangioma   9120/0
11.4. Epitheloid Haemangioendothelioma   9133/3
11.5. Angiosarcoma   9120/3
11.6. Kaposi sarcoma   9140/3
11.7. Ewing sarcoma/PNET   9364/3
11.8. Lipoma   8850/0
11.9. Angiolipoma   8861/0
11.10. Hibernoma   8880/0
11.11. Liposarcoma   8850/3
11.12. Desmoid-type fibroma   8821/1
11.13. Myofibroblastoma   8825/0
11.14. Inflammatory myofibroblastic tumour   8825/1
11.15. Benign fibrous histiocytoma   8830/0
11.16. Fibrosarcoma   8810/3
11.17. Undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma   8802/3
11.18. Leiomyoma   8890/0
11.19. Leiomyosarcoma   8890/3
11.20. Rhabdomyoma   8900/0
11.21. Rhabdomyosarcoma   8900/3
11.22. Chondroma   9220/0
11.23. Chondrosarcoma   9220/3
11.24. Osteoma   9180/0
11.25. Osteochondroma   9210/0
11.26. Osteosarcoma   9180/3
       
       
12. Melanocytic tumours    
       
12.1. Meningeal melanocytosis   8728/0
12.2. Meningeal melanocytoma   8728/1
12.3. Meningeal melanoma   8720/3
12.4. Meningeal melanomatosis   8728/3
12.5.      
       
13.
Lymphomas    
       
13.1. Diffuse large B-cell lymphoma of the CNS   9680/3
13.2. Immunodeficiency-associated lymphoma of the CNS    
13.2.1.  •  AIDS-related diffuse large B-cell lymphoma    
13.2.2.  •  EBV-positive large B-cell lymphoma, NOS    
13.2.3.  •  Lymphomatoid granulomatosis   9766/1
13.3. Intravascular large B-cell lymphoma   9712/3
13.4. Low-grade B-cell lymphoma of the CNS    
13.5. T-cell and NK/T-cell lymphoma of the CNS    
13.6. Anaplastic large cell lymphoma, ALK-positive   9714/3
13.7. Anaplastic large cell lymphoma, ALK-negative   9702/3
13.8. MALT lymphome of the dura   9699/3
       
       
14.
Histiocytic tumours    
       
14.1. Langerhans cell histiocytosis   9751/3
14.2. Erdheim-Chester disease   9750/1
14.3. Rosai-Dorfman disease    
14.4. Juvenile xanthogranuloma    
14.5. Histiocytic sarcoma   9755/3
       
       
15.
Germ cell tumours    
       
15.1. Germinoma   9064/3
15.2. Embryonal carcinoma   9070/3
15.3. Yolk sac tumour   9071/3
15.4. Chorioncarcinoma   9100/3
15.5. Teratoma   9080/1
15.5.1.  •  Mature teratoma   9080/0
15.5.2.  •  Immature teratoma   9080/1
15.6. Teratoma with malignant transformation   9084/3
15.7. Mixed germ cell tumour   9085/3
       
       
16.
Tumours of the sellar region    
       
16.1. Craniopharyngeoma  I 9650/1
16.1.1.  •  Adamantinomatous craniopharyngeoma   9351/1
16.1.2.  •  Papillary craniopharyngeoma   9352/1
16.2. Granular cell tumour of the sellar region  I 9582/0
16.3. Pituicytoma  I 9432/1
16.4. Spindle cell oncocytoma (SCO)  I 8290/0
       
       
17. Metastatic tumours    

 

 

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