Glioblastoma

Achtung! Glioblastom-Informationstag

Experten verschiedener Fachrichtungen und Kliniken informieren über aktuelle Erkenntnisse der Glioblastom-Therapie. Die Veranstaltung richtet sich bundesweit an Patienten und ihre Angehörigen.

 

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The glioblastoma (GBM) is a primary brain tumour that emerges from the glia cells. According to the WHO classification, this aggressive brain tumour is classified as WHO-grade IV.

   

Please note that the following threads of our forum are currently only available in German language.

Aktuelles aus dem Glioblastom Forum

 

Aktuelle Beiträge zum Thema Glioblastom

Antw.
Mutmacher10
Bin so traurig8
Glioblastom Behandlung mit TMZ+CCNU+Methadon2
Vierte Operation geschafft47
Wenn der Lebenspartner schwach ist28

Histology of Glioblastoma

  • features necrosis and hemorrhage
  • high poliferation and fast growth
  • very malignant

 

Epidemology of Glioblastoma

  • average age between 45 and 60, but also younger patients can be affected
  • twice as often in men

 

Symptoms of Glioblastoma

  • signs of intracranial pressure, neurological failures or epileptical seizures
  • headache
  • dizziness
  • emesis
  • vision impairment

 

Diagnosing Glioblastoma

  • very short anamnesis of weeks or a few months
  • diagnosis using MRI scan, CT scan, biopsy
  • irregularly, highly receptive contrast agent
  • central decreased contrast enhancing (hypodense center)
  • diffuse infiltration of surrounding brain tissue
  • tendency to high-volume central necoris and peritumorous edema
  • main location: cerebral hemisppheres and corpus callosum ("butterfly glioma")
  • surrounded by an expanded white matter edema
  • at diagnosis often bigger than 2 cm
  • misdiagnosis: e.g. stroke

 

Therapy of Glioblastoma

  • surgerey
  • radioherapy on tumour volume and safety margin of 2 cm
  • chemotherapy
  • clinical trial

 

Therapy of Recurrent Glioblastoma

  • renewed surgery
  • second radiotherapy
  • chemotherapy
  • clinical trial

 

Course of Glioblastoma

  • relatively fast growth with infiltration of surrounding tissue
  • recurrence even after successful surgery / therapy usually within one year

Aktuelles

Tumortherapiefelder: DHH-Stellungnahme

Lebensqualität und Tumortherapiefelder bei GBM-Patienten

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Sicht des Patienten berücksichtigen

Umdenken bei den Zielen von klinischen Studien gefordert

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Molekulare Erkenntnisse bei Gliomen

Empfehlung von Änderungen für die Klassifikation von Hirntumoren

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