Oligodendrogliomas are a type of brain tumours that are believed to originate from the oligodenrocytes of the brain or from a glial precursor cell. Similar to other gliomas, they can be divided into a low-grade and an anaplastic variant.


Please note that the following threads of our forum are currently only available in German language.

Aktuelles aus dem Oligodendrogliom Forum

Aktuelle Beiträge zum Thema Oligodendrogliom


Histology of Oligodendroglioma

    • oligodendroglioma (WHO grade II)
    • anaplastic oligodendroglioma (WHO grade III)


    Epidemiology of Oligodendroglioma


    • peak age between 35 and 50
    • in childhood around 10
    • men are a little more often affected


    Symptoms of Oligodendroglioma


    • mainly epileptic seizures as initial sign
    • symptoms of cerebral pressure (headache, nausea, emesis)
    • less frequently neurological deficits and organic psycho syndrome
    • locally caused symptoms related to increased growth

    Diagnosing Oligodendroglioma

    • diagnosis with MRT and CT
    • sometimes biopsy to confirm diagosis
    • CT to detect frequently occuring calcifications
    • heterogenous enhancement of contrast agent
    • sometimes slight enhancement of contrast agent in WHO grade II
    • diffusely infiltrating in surrounding tissue
    • often hemorrhages
    • main localisation: frontal- and temporal lobe of cerebrum


    Therapy of Oligodendroglioma


    • as complete as possible surgical removal of brain tumour
    • radiotherapy after partial surgeries and anaplastic tumours
    • chemotherapy in progressive and anaplastic tumours
    • chemotherapy also discussed for grade II tumours

    Therapy of Recurrent Oligodendroglioma

    • renewed surgery of brain tumour
    • (second) irradiation
    • chemotherapy with different agents, e.g. PCV-scheme
    • experimental therapeutic approaches


    Aftercare of Oligodendroglioma


    • first check-up 6 weeks after therapy (MRI with contrast agent)
    • WHO grade II: check-up every three months, if results are constant every 6 to 12 months
    • WHO grade III: every three months (MRI with contrast agent)


    Course of Oligodendroglioma


    • growth characteristic depends on WHO grade
    • high rate of recurrence
    • development from WHO grade II to WHO grade III possible


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